Granulocyte colony stimulating factor (G-CSF) is a molecule that carries a signal to the bone marrow, causing it to produce granulocytes and neutrophils (types of white blood cell), as well as stem cells.
Researchers have recently found that G-CSF can cause the growth of neurons (nerve cells - such as those in the brain) in young animals. A lot of scientists disagree whether neurons can grow in adult animals (or humans), and believe that damaged brain cells or other neurons cannot be replaced. However, a study1 has shown that treatment with G-CSF after a stroke improved recovery in aged rats. Treated rats survived better and showed greater improvement in mobility and memory. The scientists observed an increase in a number of neurons, which shows that neurons can be "born" even in adult animals.
This research points the way towards more effective treatment of stroke victims, and could mean an improved prognosis for many stroke patients in the future.
1 Popa-Wagner A et al. Effects of Granulocyte-Colony Stimulating Factor After Stroke in Aged Rats. Stroke 41:1027 (2010).
Source.
Researchers have recently found that G-CSF can cause the growth of neurons (nerve cells - such as those in the brain) in young animals. A lot of scientists disagree whether neurons can grow in adult animals (or humans), and believe that damaged brain cells or other neurons cannot be replaced. However, a study1 has shown that treatment with G-CSF after a stroke improved recovery in aged rats. Treated rats survived better and showed greater improvement in mobility and memory. The scientists observed an increase in a number of neurons, which shows that neurons can be "born" even in adult animals.
This research points the way towards more effective treatment of stroke victims, and could mean an improved prognosis for many stroke patients in the future.
1 Popa-Wagner A et al. Effects of Granulocyte-Colony Stimulating Factor After Stroke in Aged Rats. Stroke 41:1027 (2010).
Source.
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